Persistence of earlier HIV-1 drug resistance mutations at new treatment failure.

doi:10.1002/jmv.10246

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Article

Persistence of earlier HIV-1 drug resistance mutations at new treatment failure.

Journal of medical virology - 1 Dec 2002

Svedhem Veronica, Lindkvist Annica, Lidman Knut, Sönnerborg Anders

Abstract excerpt

The objective was to study the persistence of drug resistance mutations detected earlier at virological failure during second or third line antiretroviral therapy. Therefore, in HIV-1 infected patients, with a virological treatment failure, genotypic resistance testing was carried out before change of therapy and at the next treatment failure. The majority of primary and secondary resistance mutations persisted...

Topics

Adult
Anti-HIV Agents
Drug Resistance, Viral
Female
Genotype
HIV Infections
HIV Protease
HIV Protease Inhibitors
HIV-1
Humans
Male
Microbial Sensitivity Tests

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Mutation

Reverse Transcriptase Inhibitors

Treatment Failure

Viral Proteins

Zidovudine

Source

Open in PubMed

Identifiers

PMID: 12376953
DOI: 10.1002/jmv.10246

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-12376953-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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