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Article

Integrating phenotypic and expression profiles to map arsenic-response networks.

Genome biology - 1 Jan 2004

Haugen Astrid C, Kelley Ryan, Collins Jennifer B, Tucker Charles J, Deng Changchun, Afshari Cynthia A, Brown J Martin, Ideker Trey, Van Houten Bennett

Abstract excerpt

BACKGROUND: Arsenic is a nonmutagenic carcinogen affecting millions of people. The cellular impact of this metalloid in Saccharomyces cerevisiae was determined by profiling global gene expression and sensitivity phenotypes. These data were then mapped to a metabolic network composed of all known...

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Identifiers

PMID: 15575969
DOI: 10.1186/gb-2004-5-12-r95
PMCID: PMC545798

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15575969-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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