Article
Mutational analysis of the activator of late transcription, Alt, in the lactococcal bacteriophage TP901-1.
Archives of virology - 1 Feb 2007
Pedersen M, Hammer K
Abstract excerpt
An activator protein, Alt, synthesized during the early state of lytic infection is required for transcription of the late operon in the lactococcal phage TP901-1. In order to identify amino acid residues in the Alt protein required for activation of the TP901-1 late promoter, P(late), hydroxylamine mutagenesis was performed, resulting in almost saturating mutagenesis of alt. Twenty-three different non-functional...
Topics
- Alleles
- Amino Acid Sequence
- Amino Acid Substitution
- DNA Mutational Analysis
- Genes, Viral
- Helix-Turn-Helix Motifs
- Lactococcus lactis
- Molecular Sequence Data
- Promoter Regions, Genetic
- Transcription, Genetic
- Transcriptional Activation
- Viral Proteins