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Article

Mitochondrial inhibition of uracil-DNA glycosylase is not mutagenic.

Molecular cancer - 1 Dec 2004

Kachhap Sushant, Singh Keshav K

Abstract excerpt

BACKGROUND: Uracil DNA glycosylase (UDG) plays a major role in repair of uracil formed due to deamination of cytosine. UDG in human cells is present in both the nucleus and mitochondrial compartments. Although, UDG's role in the nucleus is well established its role in mitochondria is less clear. RESULTS: In order to identify UDG's role in the mitochondria we expressed UGI (uracil glycosylase inhibitor) a natural...

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Identifiers

PMID: 15574194
DOI: 10.1186/1476-4598-3-32
PMCID: PMC538255

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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