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Article

Targeting of mutant hogg1 in mammalian mitochondria and nucleus: effect on cellular survival upon oxidative stress.

BMC cancer - 3 Oct 2006

Chatterjee Aditi, Mambo Elizabeth, Zhang Yonggang, Deweese Theodore, Sidransky David

Abstract excerpt

BACKGROUND: Oxidative damage to mitochondrial DNA has been implicated as a causative factor in a wide variety of degenerative diseases, aging and cancer. The modified guanine, 7,8-dihydro-8-oxoguanine (also known as 8-hydroxyguanine) is one of the major oxidized bases generated in DNA by reactive oxygen species and has gained most of the attention in recent years as a marker of oxidative DNA injury and its...

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Identifiers

PMID: 17018150
DOI: 10.1186/1471-2407-6-235
PMCID: PMC1633743

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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Targeting of mutant hogg1 in mammalian mitochondria and nucleus: effect on cellular survival upon oxidative stress.PMID 17018150Read ↗

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