The apolipoprotein E polymorphism is associated with circulating C-reactive protein (the Ludwigshafen risk and cardiovascular health study)

Abstract excerpt

BACKGROUND: Statins and cholesterol absorption inhibitors lower the concentration of C-reactive protein (CRP). The genetic polymorphism of apolipoprotein (apo) E is a strong endogenous determinant of sterol homeostasis. We therefore examined the relationship of CRP to the apoE polymorphism. METHODS AND RESULTS: We studied 739 and 570 subjects with or without stable angiographic coronary artery disease (CAD),...

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