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Article

The inverse association between the apolipoprotein E ε4 allele and C-reactive protein levels is stronger in persons with obesity and diabetes.

Scandinavian journal of immunology - 1 Jan 2024

Giil Lasse Melvaer, Hanseth Silja, Bojovic Ognjen, Nordrehaug Jan Erik, Ueland Per Magne, Meyer Klaus, Tell Grethe S

Abstract excerpt

BACKGROUND: C-reactive protein (CRP) is lower in patients who carry the apolipoprotein E epsilon 4 allele variant (APOEε4) of the APOE gene. This could however be explained by other factors observed in APOEε4 carriers, such as lower body mass index (BMI), possibly less diabetes and more use of statins, all associated with CRP concentrations. OBJECTIVES: To assess the association between CRP and APOEε4 stratified...

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PMID: 37801334
DOI: 10.1111/sji.13323

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