Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Apo E4 and lipoprotein-associated phospholipase A2 synergistically increase cardiovascular risk.

Atherosclerosis - 1 Jul 2012

Gungor Zeynep, Anuurad Erdembileg, Enkhmaa Byambaa, Zhang Wei, Kim Kyoungmi, Berglund Lars

Abstract excerpt

OBJECTIVE: Apolipoprotein E (apoE) has been implicated as conveying increased risk for coronary artery disease (CAD). Previous studies suggest a role of apoE as a modulator of immune response and inflammatory properties. We hypothesized that the presence of apo E4 is associated with an increased inflammatory burden in subjects with CAD as compared to subjects without CAD. METHODS: ApoE genotypes, systemic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 1-Alkyl-2-acetylglycerophosphocholine Esterase
Share to C-Reactive Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Coronary Angiography

Share to Fibrinogen

Share to Inflammation Mediators

Share to Phospholipases A2

Share to Serum Amyloid A Protein

Share to Serum Amyloid P-Component

Source

Open in PubMed Open full text

Identifiers

PMID: 22632920
DOI: 10.1016/j.atherosclerosis.2012.04.021
PMCID: PMC3389284

Genes

CAD
CRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Apo E4 and lipoprotein-associated phospholipase A2 synergistically increase cardiovascular risk.PMID 22632920Read ↗

Apolipoprotein E polymorphism is associated with both carotid and coronary atherosclerosis in patients with coronary artery disease.Semantic proximity Read ↗

Lipoprotein(a): An independent, genetic, and causal factor for cardiovascular disease and acute myocardial infarctionSemantic proximity Read ↗

The apolipoprotein E polymorphism is associated with circulating C-reactive protein (the Ludwigshafen risk and cardiovascular health study)Semantic proximity Read ↗

Apolipoprotein E-ε2 and Resistance to Atherosclerosis in Midlife: The PESA Observational Study.Semantic proximity Read ↗

Genetic and Mechanistic Insights into the Modulation of Circulating Lipoprotein (a) Concentration by Apolipoprotein E Isoforms.Semantic proximity Read ↗

The association between APOE allele variants and inflammatory markers in a large-scale Chinese population.Semantic proximity Read ↗

Association of Apolipoprotein E (APOE) Polymorphisms With Serological Lipid and Inflammatory MarkersSemantic proximity Read ↗

Association of APOE polymorphisms with serological lipid and inflammatory markersSemantic proximity Read ↗

Integrated role of two apoliprotein E polymorphisms on apolipoprotein B levels and coronary artery disease in a biethnic population.Semantic proximity Read ↗

Association between apolipoprotein E polymorphisms and premature coronary artery disease: a meta-analysis.Semantic proximity Read ↗

ApoE genotype, cardiovascular risk and responsiveness to dietary fat manipulation.Semantic proximity Read ↗

Apolipoprotein E gene polymorphism: effects on plasma lipids and risk of type 2 diabetes and coronary artery disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.