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Article

APOE Genotypes Modulate Inflammation Independently of Their Effect on Lipid Metabolism.

International journal of molecular sciences - 26 Oct 2022

Civeira-Marín María, Cenarro Ana, Marco-Benedí Victoria, Bea Ana M, Mateo-Gallego Rocío, Moreno-Franco Belén, Ordovás José M, Laclaustra Martín, Civeira Fernando, Lamiquiz-Moneo Itziar

Abstract excerpt

The association between APOE genotypes and cardiovascular disease (CVD) is partially mediated by LDL-cholesterol concentration but persists after adjusting for lipid levels and other cardiovascular risk factors. Data from the Aragon Workers Health Study (AWHS) (n = 4159) and the Lipid Unit at the Hospital Universitario Miguel Servet (HUMS) (n = 3705) were used to investigate the relationship between C-reactive...

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Identifiers

PMID: 36361733
DOI: 10.3390/ijms232112947
PMCID: PMC9656824

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