Article
Apolipoprotein E genotype is related to plasma levels of C-reactive protein and lipids and to longevity in nonagenarians.
Clinical endocrinology - 1 Mar 2006
Rontu Riikka, Ojala Petri, Hervonen Antti, Goebeler Sirkka, Karhunen Pekka J, Nikkilä Matti, Kunnas Tarja, Jylhä Marja, Eklund Carita, Hurme Mikko, Lehtimäki Terho
Abstract excerpt
OBJECTIVE: Apolipoprotein E (APOE) genotype is a regulator of hepatic lipoprotein metabolisms and has been linked with longevity. The relationship between APOE genotype and plasma C-reactive protein (CRP), which is produced by the liver during inflammation, has not been studied in nonagenarians. The aim of the present study was to establish whether APOE genotype is related to plasma concentrations of CRP and...
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