Article
Genome signatures of colon carcinoma cell lines.
Cancer genetics and cytogenetics - 1 Dec 2004
Kleivi Kristine, Teixeira Manuel R, Eknaes Mette, Diep Chieu B, Jakobsen Kjetill S, Hamelin Richard, Lothe Ragnhild A
Abstract excerpt
In cancer biology, cell lines are often used instead of primary tumors because of their widespread availability and close reflection of the in vivo state. Cancer is a genetic disease, commonly caused by small- and large-scale DNA rearrangements. Therefore, it is essential to know the genomic profiles of tumor cell lines to enable their correct and efficient use as experimental tools. Here, we present a...
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