Article
Genotyping technologies: application to biotransformation enzyme genetic polymorphism screening.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2005
Romkes Marjorie, Buch Shama C
Abstract excerpt
Pharmacogenomics encompasses several major areas: the study of polymorphic variations in drug response and disease susceptibility, identification of the effects of drugs/xenobiotics at the genomic level, and genotype/phenotype associations. The most common type of human genetic variations is single-nucleotide polymorphisms (SNPs). Several novel approaches to detection of SNPs are currently available. The range of...
Topics
- Biotransformation
- Enzymes
- Genetic Techniques
- Genetic Testing
- Genotype
- Humans
- Pharmacogenetics
- Polymorphism, Single Nucleotide
