Article
AmpliChip CYP450 GeneChip: a new gene chip that allows rapid and accurate CYP2D6 genotyping.
Therapeutic drug monitoring - 1 Oct 2006
Heller Tanja, Kirchheiner Julia, Armstrong Victor W, Luthe Hilmar, Tzvetkov Mladen, Brockmöller Jürgen, Oellerich Michael
Abstract excerpt
Methods for Cytochrome P450-2D6 (CYP2D6) genotyping are often time-consuming and laborious, which can restrict their use in pretherapeutic screening programs. Gene chip technology could overcome this problem. The aim of this study was to evaluate CYP2D6 genotyping by a new improved gene chip compared to a PCR-RFLP method. AmpliChip CYP450 GeneChip(R) (AmpliChip) is a microarray hybridization method for genotyping...
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