Article
Allele 2 of the interleukin-1 receptor antagonist gene is associated with early gastric cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Dec 2004
Glas Jürgen, Török Helga-Paula, Schneider Agnes, Brünnler Günter, Kopp Reinhard, Albert Ekkehard D, Stolte Manfred, Folwaczny Christian
Abstract excerpt
PURPOSE: In advanced gastric cancer (tumor stages T2-T4), associations with polymorphisms of the interleukin-1 (IL-1) gene cluster have been made. In early-stage gastric cancer, which we defined as adenocarcinoma confined to the mucosa or submucosa (stage T1), the role of host genetic susceptibility remains to be determined. PATIENTS AND METHODS: Eighty-eight patients with early-stage gastric cancer (stage T1, 77...
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