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Article

Interleukin-1B and interleukin-1 receptor antagonist gene polymorphisms are not associated with premalignant gastric conditions: a combined haplotype analysis.

European journal of gastroenterology & hepatology - 1 Oct 2010

Kupcinskas Limas, Wex Thomas, Kupcinskas Juozas, Leja Marcis, Ivanauskas Audrius, Jonaitis Laimas Virgilijus, Janciauskas Dainius, Kiudelis Gediminas, Funka Konrads, Sudraba Agnese, Chiu Han-Mo, Lin Jaw-Town, Malfertheiner Peter

Abstract excerpt

OBJECTIVE: Contradictory results have been reported about the role of interleukin-1B (IL1B) and IL1 receptor antagonist (IL1RN) alleles in gastric carcinogenesis. Here, IL1B and IL1RN polymorphisms were analyzed as genotypes and haplotypes in relation to the presence of atrophic gastritis (AG) and intestinal metaplasia in the stomach. METHODS: Two hundred and seventy-eight patients (212 Caucasians and 66 Asians)...

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Identifiers

PMID: 20631624
DOI: 10.1097/MEG.0b013e32833cf3d5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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