Article
Increased risk of noncardia gastric cancer associated with proinflammatory cytokine gene polymorphisms.
Gastroenterology - 1 May 2003
El-Omar Emad M, Rabkin Charles S, Gammon Marilie D, Vaughan Thomas L, Risch Harvey A, Schoenberg Janet B, Stanford Janet L, Mayne Susan T, Goedert James, Blot William J, Fraumeni Joseph F, Chow Wong-Ho
Abstract excerpt
BACKGROUND & AIMS: Genetic variations in proinflammatory and anti-inflammatory cytokine genes influence individual response to carcinogenic exposures. Polymorphisms in interleukin (IL)-1 beta and its endogenous receptor antagonist are associated with risk of Helicobacter pylori-related gastric cancer. The aim of this study was to evaluate the role of proinflammatory cytokine gene polymorphisms in gastric and...
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