Article
The course of gastric cancer following surgery is associated with genetic variations of the interleukin-1 receptor antagonist and interleukin-1β.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association - 1 Jan 2015
van der Ploeg Anke H, Kumpf Oliver, Seelow Evelyn, Almanza Luis C Berrocal, Schlag Peter M, Schumann Ralf R, Hamann Lutz
Abstract excerpt
BACKGROUND: Inflammation, especially the cytokine response of the IL-1 family, has been shown to influence susceptibility to gastric cancer. In addition, several other pro-inflammatory cytokines have been demonstrated to influence metastasis and resistance to chemotherapy. Therefore, genetic variations within these genes may not only affect susceptibility but also influence the outcome of gastric cancer patients....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.