Article
Are single nucleotide polymorphisms of the immunoglobulin A Fc receptor gene associated with allergic asthma?
International archives of allergy and immunology - 1 Dec 2004
Jasek Monika, Obojski Andrzej, Mańczak Maria, Wiśniewski Andrzej, Winiarska Beata, Małolepszy Józef, Jutel Marek, Łuszczek Wioleta, Kuśnierczyk Piotr
Abstract excerpt
BACKGROUND: Eosinophils are important components of allergic inflammation. The immunoglobulin A (IgA) Fc receptor (FcalphaRI), encoded by the FCAR gene, is a possible candidate for eosinophil activation at mucosal surfaces, where IgA is abundant. Both elevated cell surface expression of FcalphaRI...
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