Functional Fcgamma receptor polymorphisms are associated with human allergy.

doi:10.1371/journal.pone.0089196

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Article

Functional Fcgamma receptor polymorphisms are associated with human allergy.

PloS one - 1 Jan 2014

Wu Jianming, Lin Rui, Huang Jinhai, Guan Weihua, Oetting William S, Sriramarao P, Blumenthal Malcolm N

Abstract excerpt

OBJECTIVE: IgG Fc receptors (FcγRs) play important roles in immune responses. It is not clear whether FcγR receptors play a role in human asthma and allergy. The aim of current study was to investigate whether functional single nucleotide polymorphisms (SNPs) of FcγR genes (FCGR) are associated with human asthma and allergy. METHODS: Functional SNPs of FCGR2A (FcγRIIA-131His>Arg, rs1801274), FCGR2B...

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Identifiers

PMID: 24586589
DOI: 10.1371/journal.pone.0089196
PMCID: PMC3931680

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