Article
Investigation of Fc Receptor-Like 3 (FCRL-3) Gene Polymorphism (rs7528684) with Susceptibility to Allergic Asthma in Iranian North-Western Azeri Population.
Clinical laboratory - 1 Jul 2017
Aslanian-Kalkhoran Lida, Elieh-Ali-Komi Daniel, Sadeghi-Shabestari Mahnaz, Shanebandi Dariush, Babaloo Zohreh, Razavi Alireza, Sadigh-Eteghad Saeed, Kazemi Tohid
Abstract excerpt
BACKGROUND: Asthma is a clinical setting in which multiple cellular and molecular mechanisms are involved. Additionally, increasing genetic studies have provided evidence that single nucleotide polymorphisms (SNPs) in asthma relevant genes confer susceptibility to the disease. Fc receptor-like (FCRL) 3, a transmembrane molecule basically involved in B-cell signaling, mediates immune-disorders including allergy....
Topics
- Asthma
- Case-Control Studies
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Humans
- Hypersensitivity
- Iran
- Polymorphism, Single Nucleotide
- Receptors, Fc