Article
A Nonsynonymous FCER1B SNP is Associated with Risk of Developing Allergic Rhinitis and with IgE Levels.
Scientific reports - 21 Jan 2016
Amo Gemma, García-Menaya Jesús, Campo Paloma, Cordobés Concepción, Plaza Serón M Carmen, Ayuso Pedro, Esguevillas Gara, Blanca Miguel, Agúndez Jose A G, García-Martín Elena
Abstract excerpt
Allergic rhinitis is associated with elevated serum IgE levels. IgE response is mediated by the high-affinity IgE receptor (FcεRI), which is polymorphic. Studies analyzing the association between allergic rhinitis and FcεRI variants have been conducted with controversial results. The objective of this study is to analyze, in 1,041 individuals, the putative clinical association of allergic rhinitis with common...
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