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Article

IL4RA gene expression in relation to I50V, Q551R and C-3223T polymorphisms.

Advances in clinical and experimental medicine : official organ Wroclaw Medical University - 1 Jan 2021

Danielewicz Hanna, Dębińska Anna, Drabik-Chamerska Anna, Kalita Danuta, Boznański Andrzej

Abstract excerpt

BACKGROUND: Interleukin 4 (IL-4) and its receptor play important roles in the pathologies of asthma and atopy. The alpha subunit of the IL-4 receptor (IL-4RA) is included in 2 types of receptors which have different modulatory effects on immune responses. This distinct pattern reflects involvement in the immunopathology of both asthma and atopy. A number of studies have proven the association between IL4RA gene...

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Share to Asthma and respiratory diseases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Hypersensitivity, Immediate

Share to Interleukin-4 Receptor alpha Subunit

Share to Leukocytes, Mononuclear

Share to Pediatric health and respiratory diseases

Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 33529503
DOI: 10.17219/acem/127031

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