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Article

Acetylation regulates subcellular localization of the Wnt signaling nuclear effector POP-1.

Genes & development - 15 Mar 2003

Gay Frédérique, Calvo Dominica, Lo Miao-Chia, Ceron Julian, Maduro Morris, Lin Rueyling, Shi Yang

Abstract excerpt

Lymphoid enhancer factor/T-cell factor (LEF/TCF) are transcription factors that mediate the Wnt signaling pathway, and have crucial roles during embryonic development in various organisms. Here we report that acetylation enhances nuclear retention of POP-1, the Caenorhabditis elegans LEF/TCF homolog, through increasing nuclear import and blocking nuclear export. We identify three lysines that are acetylated in...

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Identifiers

PMID: 12651889
DOI: 10.1101/gad.1042403
PMCID: PMC196022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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