Article
Role of the constitutive androstane receptor in xenobiotic-induced thyroid hormone metabolism.
Endocrinology - 1 Mar 2005
Qatanani Mohammed, Zhang Jun, Moore David D
Abstract excerpt
The induction of hepatic drug metabolizing enzymes alters not only the metabolism of the xenobiotic substances that induce them but also the metabolism of various endogenous hormones. The xenobiotic receptor constitutive androstane receptor (CAR) (NR1I3) mediates the well-studied induction of CYP...
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