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Article

ATP-2 Interacts with the PLAT Domain of LOV-1 and Is Involved in <i>Caenorhabditis elegans</i> Polycystin Signaling

24 Nov 2004

Abstract excerpt

Caenorhabditis elegans is a powerful model to study the molecular basis of autosomal dominant polycystic kidney disease (ADPKD). ADPKD is caused by mutations in the polycystic kidney disease (PKD)1 or PKD2 gene, encoding polycystin (PC)-1 or PC-2, respectively. The C. elegans polycystins LOV-1 and PKD-2 are required for male mating behaviors and are localized to sensory cilia. The function of the evolutionarily...

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PMID: 15563610
DOI: 10.1091/mbc.e04-09-0851

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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ATP-2 Interacts with the PLAT Domain of LOV-1 and Is Involved in <i>Caenorhabditis elegans</i> Polycystin SignalingPMID 15563610Read ↗

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