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Article

Polycystin-2 accelerates Ca2+ release from intracellular stores in Caenorhabditis elegans.

Cell calcium - 1 Jun 2005

Koulen Peter, Duncan R Scott, Liu Jiyuan, Cohen Nancy E, Yannazzo Jo-Ann S, McClung Nathalie, Lockhart Courtney L, Branden Michael, Buechner Matthew

Abstract excerpt

Polycystin-2, a member of the TRP family of calcium channels, is encoded by the human PKD2 gene. Mutations in that gene can lead to swelling of nephrons into the fluid-filled cysts of polycystic kidney disease. In addition to expression in tubular epithelial cells, human polycystin-2 is found in muscle and neuronal cells, but its cell biological function has been unclear. A homologue in Caenorhabditis elegans is...

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Source

Identifiers

PMID: 15862350
DOI: 10.1016/j.ceca.2005.03.003

Genes

PKD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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