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Article

Meta-analysis investigating the role of interleukin-6 mediated inflammation in type 2 diabetes.

EBioMedicine - 1 Nov 2020

Bowker Nicholas, Shah Rupal L, Sharp Stephen J, Luan Jian'an, Stewart Isobel D, Wheeler Eleanor, Ferreira Manuel A R, Baras Aris, Wareham Nicholas J, Langenberg Claudia, Lotta Luca A

Abstract excerpt

BACKGROUND: Evidence from animal models and observational epidemiology points to a role for chronic inflammation, in which interleukin 6 (IL-6) is a key player, in the pathophysiology of type 2 diabetes (T2D). However, it is unknown whether IL-6 mediated inflammation is implicated in the pathophysiology of T2D. METHODS: We performed a meta-analysis of 15 prospective studies to investigate associations between...

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Identifiers

PMID: 33096487
DOI: 10.1016/j.ebiom.2020.103062
PMCID: PMC7581887

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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