Article
Two isoforms of eIF-5A in chick embryo. Isolation, activity, and comparison of sequences of the hypusine-containing proteins.
The Journal of biological chemistry - 25 Mar 1992
Wolff E C, Kinzy T G, Merrick W C, Park M H
Abstract excerpt
Eukaryotic translation initiation factor 5A (eIF-5A) (older terminology, eIF-4D) is unique in that it contains the unusual amino acid hypusine (N epsilon-(4-amino-2-hydroxybutyl)lysine). Hypusine is formed by a post-translational event in which a specific lysine residue is modified by a structura...
Topics
- Amino Acid Sequence
- Animals
- Cells, Cultured
- Chick Embryo
- Chickens
- Chromatography, DEAE-Cellulose
- Chromatography, Gel
- Chromatography, Ion Exchange
- Electrophoresis, Gel, Two-Dimensional
- Fibroblasts
- Genetic Variation
- Humans
- Lysine
- Male
- Molecular Sequence Data
- Peptide Initiation Factors
- Peptide Mapping
- Putrescine