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Article

The effect of hypusine modification on the intracellular localization of eIF5A.

Biochemical and biophysical research communications - 12 Jun 2009

Lee Seung Bum, Park Jong Hwan, Kaevel Jörn, Sramkova Monika, Weigert Roberto, Park Myung Hee

Abstract excerpt

Eukaryotic translation initiation factor 5A (eIF5A) is a highly conserved protein essential for eukaryotic cell proliferation and is the only protein containing hypusine, [N(epsilon)-(4-amino-2-hydroxybutyl)lysine]. eIF5A is activated by the post-translational synthesis of hypusine. eIF5A also undergoes an acetylation at specific Lys residue(s). In this study, we have investigated the effect of hypusine...

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Identifiers

PMID: 19379712
DOI: 10.1016/j.bbrc.2009.04.049
PMCID: PMC2737708

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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