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Article

Tumor-prone phenotype of the DDB2-deficient mice.

Oncogene - 13 Jan 2005

Yoon Taewon, Chakrabortty Amit, Franks Roberta, Valli Ted, Kiyokawa Hiroaki, Raychaudhuri Pradip

Abstract excerpt

DDB2 is an essential subunit of the damaged-DNA recognition factor DDB, which is involved in global genomic repair in human cells. Moreover, DDB2 is mutated in the repair-deficiency disease xeroderma pigmentosum (Group E). Expression of DDB2 in human cells is induced by P53, BRCA1 and by ionizing radiation. The DDB2 protein associates with transcriptional activator and coactivator proteins. In addition, DDB2 in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15558025
DOI: 10.1038/sj.onc.1208211
PMCID: PMC2892891

Genes

DDB2
BRCA1
CPD
DDB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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