Article
Different aspects of gliosis in retinal Muller glia can be induced by CNTF, insulin, and FGF2 in the absence of damage.
Molecular vision - 22 Dec 2004
Fischer Andy J, Omar Ghezal, Eubanks Jim, McGuire Christopher Roger, Dierks Blair Dorian, Reh Thomas A
Abstract excerpt
PURPOSE: In response to acute damage, Muller glia in the retina have been shown to dramatically alter their expression of filamentous proteins. Since damaged retinal cells are known to produce growth factors such as insulin-like growth factor (IGF), ciliary neurotrophic factor (CNTF) and fibroblast growth factor (FGF), the altered expression of filaments in Muller glia in response to retinal damage may be induced...
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