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Article

Maintenance of the keratocyte phenotype during cell proliferation stimulated by insulin.

The Journal of biological chemistry - 23 Sept 2005

Musselmann Kurt, Alexandrou Bridgette, Kane Bradley, Hassell John R

Abstract excerpt

Keratocytes normally express high levels of aldehyde dehydrogenase and keratocan. They proliferate and lose their keratocyte markers when they become fibroblastic during corneal wound healing. Keratocytes cultured in fetal bovine serum also become fibroblastic, proliferate, and lose these markers. In this report, we studied the effects of three serum growth factors, fibroblast growth factor-2, insulin, and...

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Source

Identifiers

PMID: 16169858
DOI: 10.1074/jbc.M504724200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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