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Article

Phenotypic expression of IGF binding protein transcripts in muscle, in vitro and in vivo.

Biochemical and biophysical research communications - 24 Jun 2000

Bayol S, Loughna P T, Brownson C

Abstract excerpt

The actions of the insulin-like growth factors (IGF-I and IGF-II) which are essential components of skeletal muscle growth are mediated via their receptors and modulated by six binding proteins (IGFBPs). We studied IGFBP transcripts in C2C12 cell cultures and in adult control and denervated gastrocnemius muscle. IGFBP-2, -4, -5, and -6 were detected in C2C12 cells. IGFBP-6 mRNA levels remained unchanged, IGFBP-2...

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Identifiers

PMID: 10873599
DOI: 10.1006/bbrc.2000.2667

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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