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Article

Insulin‐like growth factor‐I (IGF‐i) stimulates protein synthesis and collagen gene expression in monolayer and lattice cultures of fibroblasts

1 Aug 1992

Abstract excerpt

Fibroblasts cultivated in three-dimensional tissue-like matrices are characterized by a slowed metabolism and a decrease of protein synthesis, unless they are submitted to physical tensions. We checked the effects of insulin like growth factor-I (IGF-I), known as a potent stimulator of mitogenesis and protein synthesis for many cell types, in various models of cultures: confluent monolayers, collagen lattices,...

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Identifiers

PMID: 1639869
DOI: 10.1002/jcp.1041520221

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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