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Article

Contribution of transmembrane regions to ATP-gated P2X2 channel permeability dynamics.

The Journal of biological chemistry - 18 Feb 2005

Khakh Baljit S, Egan Terrance M

Abstract excerpt

ATP-gated P2X(2) channels undergo activation-dependent permeability increases as they proceed from the selective I(1) state to the I(2) state that is readily permeable to organic cations. There are two main models about how permeability changes may occur. The first proposes that permeability change-competent P2X channels are clustered or redistribute to form such regions in response to ATP. The second proposes...

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Identifiers

PMID: 15556949
DOI: 10.1074/jbc.M411324200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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