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Article

Voltage- and [ATP]-dependent gating of the P2X(2) ATP receptor channel.

The Journal of general physiology - 1 Jan 2009

Fujiwara Yuichiro, Keceli Batu, Nakajo Koichi, Kubo Yoshihiro

Abstract excerpt

P2X receptors are ligand-gated cation channels activated by extracellular adenosine triphosphate (ATP). Nonetheless, P2X(2) channel currents observed during the steady-state after ATP application are known to exhibit voltage dependence; there is a gradual increase in the inward current upon hyperpolarization. We used a Xenopus oocyte expression system and two-electrode voltage clamp to analyze this "activation"...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19114637
DOI: 10.1085/jgp.200810002
PMCID: PMC2606937

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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