Article
Polar residues in the second transmembrane domain of the rat P2X2 receptor that affect spontaneous gating, unitary conductance, and rectification.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 11 Nov 2009
Cao Lishuang, Broomhead Helen E, Young Mark T, North R Alan
Abstract excerpt
Membrane ion channels activated by extracellular ATP (P2X receptors) are widely distributed in the nervous system. Their molecular architecture is fundamentally distinct from that of the nicotinic or glutamate receptor families. We have measured single-channel currents, spontaneous gating, and re...
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