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Article

A CRM1-dependent nuclear export pathway is involved in the regulation of IRF-5 subcellular localization.

The Journal of biological chemistry - 28 Jan 2005

Lin Rongtuan, Yang Long, Arguello Meztli, Penafuerte Claudia, Hiscott John

Abstract excerpt

Interferon regulatory factors (IRFs) are involved in gene regulation in many biological processes including the antiviral, growth regulatory, and immune modulatory functions of the interferon system. Several studies have demonstrated that IRF-3, IRF-5, and IRF-7 specifically contribute to the innate antiviral response to virus infection. It has been reported that virus-specific phosphorylation leads to IRF-5...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15556946
DOI: 10.1074/jbc.M408452200

Genes

NES
TBK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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