Article
Essential role of interferon regulatory factor 3 in direct activation of RANTES chemokine transcription.
Molecular and cellular biology - 1 Feb 1999
Lin R, Heylbroeck C, Genin P, Pitha P M, Hiscott J
Abstract excerpt
Localized and systemic cytokine production in virus-infected cells play an important role in the outcome of viral infection and pathogenicity. Activation of the interferon regulatory factors (IRF) in turn is a critical mediator of cytokine gene transcription. Recent studies have focused on the 55...
Topics
- Base Sequence
- Binding Sites
- Cell Line
- Chemokine CCL5
- DNA
- DNA Primers
- DNA-Binding Proteins
- Humans
- Interferon Regulatory Factor-3
- Mutation
- NF-kappa B
- Promoter Regions, Genetic
- Respirovirus
- Tetracycline
- Transcription Factors
- Transcriptional Activation
- Transfection