Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Nucleolar trafficking is essential for nuclear export of intronless herpesvirus mRNA

27 Sept 2006

Abstract excerpt

The nucleolus is the largest subnuclear structure and is plurifunctional in nature. Here, we demonstrate that nucleolar localization of a key herpesvirus regulatory protein is essential for its role in virus mRNA nuclear export. The herpesvirus saimiri ORF57 protein is a nucleocytoplasmic shuttle protein that is conserved in all herpesviruses and orchestrates the nuclear export of viral intronless mRNAs. We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to Herpesvirus Infections and Treatments
Share to Viral-associated cancers and disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17005724
DOI: 10.1073/pnas.0604890103

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Nucleolar trafficking is essential for nuclear export of intronless herpesvirus mRNAPMID 17005724Read ↗

The prototype γ-2 herpesvirus nucleocytoplasmic shuttling protein, ORF 57, transports viral RNA through the cellular mRNA export pathwaySemantic proximity Read ↗

Mutation of a C-terminal motif affects Kaposi's sarcoma-associated herpesvirus ORF57 RNA binding, nuclear trafficking, and multimerization.Semantic proximity Read ↗

The Evolutionarily Conserved Kaposi's Sarcoma-associated Herpesvirus ORF57 Protein Interacts with REF Protein and Acts as an RNA Export FactorSemantic proximity Read ↗

Recruitment of the Complete hTREX Complex Is Required for Kaposi's Sarcoma–Associated Herpesvirus Intronless mRNA Nuclear Export and Virus ReplicationSemantic proximity Read ↗

The human cytomegalovirus regulatory protein UL69 and its effect on mRNA exportSemantic proximity Read ↗

Molecular mechanism underlying selective inhibition of mRNA nuclear export by herpesvirus protein ORF10Semantic proximity Read ↗

Kaposi's Sarcoma-Associated Herpesvirus ORF57 Protein Binds and Protects a Nuclear Noncoding RNA from Cellular RNA Decay PathwaysSemantic proximity Read ↗

The Structure-to-Function Relationships of Gammaherpesvirus-Encoded Long Non-Coding RNAs and their Contributions to Viral PathogenesisSemantic proximity Read ↗

Kaposi's sarcoma-associated herpesvirus ORF57 in viral RNA processingSemantic proximity Read ↗

Retroviral mRNA nuclear export elements regulate protein function and virion assemblySemantic proximity Read ↗

A molecular switch orchestrates the nuclear export of human messenger RNASemantic proximity Read ↗

Competitive and Cooperative Interactions Mediate RNA Transfer from Herpesvirus Saimiri ORF57 to the Mammalian Export Adaptor ALYREFSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.