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Article

Thermodynamics of apocalmodulin and nitric oxide synthase II peptide interaction.

FEBS letters - 19 Nov 2004

Censarek Petra, Beyermann Michael, Koch Karl-Wilhelm

Abstract excerpt

The Ca2+-free form of calmodulin (CaM), apocalmodulin (ApoCaM), regulates a variety of target proteins including nitric oxide synthase II (NOS-II). The CaM-binding site of NOS-II can bind ApoCaM with high affinity. Substitution of hydrophobic amino acids by charged amino acids at crucial positions 3, 9 and 13 within the CaM-binding motif did not abolish the ApoCaM interaction that occurred with significant...

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Identifiers

PMID: 15556629
DOI: 10.1016/j.febslet.2004.10.048

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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