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Article

Apocalmodulin and Ca2+ calmodulin-binding sites on the CaV1.2 channel.

Biophysical journal - 1 Sept 2003

Tang Wei, Halling D Brent, Black D J, Pate Patricia, Zhang Jia-Zheng, Pedersen Steen, Altschuld Ruth A, Hamilton Susan L

Abstract excerpt

The cardiac L-type voltage-dependent calcium channel is responsible for initiating excitation-contraction coupling. Three sequences (amino acids 1609-1628, 1627-1652, and 1665-1685, designated A, C, and IQ, respectively) of its alpha(1) subunit contribute to calmodulin (CaM) binding and Ca(2+)-de...

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Identifiers

PMID: 12944271
DOI: 10.1016/s0006-3495(03)74586-x
PMCID: PMC1303330

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12944271-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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