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Article

Plasminogen activator inhibitor 1 expression in platelets is not influenced by the 4G/5G promoter polymorphism.

Thrombosis research - 1 Jan 2008

Brogren Helén, Wallmark Karin, Jern Sverker, Karlsson Lena

Abstract excerpt

In the present study we investigated the influence of the 4G/5G promoter polymorphism of the PAI-1 gene on the levels of PAI-1 mRNA and protein in platelets. After a screening of healthy male subjects, thirty-eight subjects homozygote for either the 4G or 5G allele were investigated. mRNA levels were quantified by real-time PCR and PAI-1 antigen in platelets and plasma was analysed by ELISA. The platelet PAI-1...

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Identifiers

PMID: 17884148
DOI: 10.1016/j.thromres.2007.07.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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