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Article

Candida albicans PLD I activity is required for full virulence.

Medical mycology - 1 Oct 2004

Dolan Joseph W, Bell A Cheria, Hube Bernhard, Schaller Martin, Warner Thomas F, Balish Edward

Abstract excerpt

Phospholipase D1 (PLD1) mutants of Candida albicans are defective in important in vivo and in vitro virulence factors. PLD1 mutants colonize the murine alimentary tract as well as PLD1 sufficient strains. In comparison to PLD1 sufficient strains, the PLD1 mutants: (i) are unable to survive in internal organs after intravenous challenge; (ii) do not decrease the body weights of mice after oral challenge; and (iii)...

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Share to Candida albicans
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gene Expression Regulation, Fungal

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Source

Identifiers

PMID: 15552646
DOI: 10.1080/13693780410001657162

Genes

PLD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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