Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inactivation of the phospholipase B gene PLB5 in wild-type Candida albicans reduces cell-associated phospholipase A2 activity and attenuates virulence.

International journal of medical microbiology : IJMM - 1 Oct 2006

Theiss Stephanie, Ishdorj Ganchimeg, Brenot Audrey, Kretschmar Marianne, Lan Chung-Yu, Nichterlein Thomas, Hacker Jörg, Nigam Santosh, Agabian Nina, Köhler Gerwald A

Abstract excerpt

Phospholipases are critical for modification and redistribution of lipid substrates, membrane remodeling and microbial virulence. Among the many different classes of phospholipases, fungal phospholipase B (Plb) proteins show the broadest range of substrate specificity and hydrolytic activity, hydrolyzing acyl ester bonds in phospholipids and lysophospholipids and further catalyzing lysophospholipase-transacylase...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Candida albicans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Candidiasis

Share to Gene Expression Profiling

Share to Multigene Family

Share to Phospholipases A

Share to Phospholipases A2

Share to Virulence

Source

Open in PubMed Open full text

Identifiers

PMID: 16759910
DOI: 10.1016/j.ijmm.2006.03.003
PMCID: PMC2481510

Genes

GPI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inactivation of the phospholipase B gene PLB5 in wild-type Candida albicans reduces cell-associated phospholipase A2 activity and attenuates virulence.PMID 16759910Read ↗

Potential Role of Phospholipases in Virulence and Fungal PathogenesisSemantic proximity Read ↗

Cloning and Disruption of caPLB1, a Phospholipase B Gene Involved in the Pathogenicity of Candida albicansSemantic proximity Read ↗

Potential Role of Phospholipases in Virulence and Fungal PathogenesisSemantic proximity Read ↗

Functional analysis of the phospholipase C gene CaPLC1 and two unusual phospholipase C genes, CaPLC2 and CaPLC3, of Candida albicans.Semantic proximity Read ↗

Secretion of cryptococcal phospholipase B1 (PLB1) is regulated by a glycosylphosphatidylinositol (GPI) anchor.Semantic proximity Read ↗

Genetic characterization of a phospholipase C gene from Candida albicans: presence of homologous sequences in Candida species other than Candida albicansSemantic proximity Read ↗

The phosphatome of opportunistic pathogen Candida speciesSemantic proximity Read ↗

Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformansSemantic proximity Read ↗

Phospholipase PlaB of Legionella pneumophila Represents a Novel Lipase FamilySemantic proximity Read ↗

A family of glycosylphosphatidylinositol-linked aspartyl proteases is required for virulence of Candida glabrata.Semantic proximity Read ↗

A serine/threonine protein phosphatase-like protein, CaPTC8, from Candida albicans defines a new PPM subfamily.Semantic proximity Read ↗

A Genome-Wide Functional Genomics Approach Identifies Susceptibility Pathways to Fungal Bloodstream Infection in HumansSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.