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Article

Roles of Elm1 in antifungal susceptibility and virulence in Candida glabrata.

Scientific reports - 17 Jun 2020

Ito Yuya, Miyazaki Taiga, Tanaka Yutaka, Suematsu Takashi, Nakayama Hironobu, Morita Akihiro, Hirayama Tatsuro, Tashiro Masato, Takazono Takahiro, Saijo Tomomi, Shimamura Shintaro, Yamamoto Kazuko, Imamura Yoshifumi, Izumikawa Koichi, Yanagihara Katsunori, Kohno Shigeru, Mukae Hiroshi

Abstract excerpt

Elm1 is a serine/threonine kinase involved in multiple cellular functions, including cytokinesis, morphogenesis, and drug resistance in Saccharomyces cerevisiae; however, its roles in pathogenic fungi have not been reported. In this study, we created ELM1-deletion, ELM1-reconstituted, ELM1-overexpression, and ELM1-kinase-dead strains in the clinically important fungal pathogen Candida glabrata and investigated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32555245
DOI: 10.1038/s41598-020-66620-7
PMCID: PMC7299981

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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