Article
The role and relevance of phospholipase D1 during growth and dimorphism of Candida albicans.
Microbiology (Reading, England) - 1 Apr 2001
Hube Bernhard, Hess Daniela, Baker Carol A, Schaller Martin, Schäfer Wilhelm, Dolan Joseph W
Abstract excerpt
The phosphatidylcholine-specific phospholipase D1 (PLD1) in Saccharomyces cerevisiae is involved in vesicle transport and is essential for sporulation. The gene encoding the homologous phospholipase D1 from Candida albicans (PLD1) was used to study the role of PLD1 in this pathogenic fungus. In vitro and in vivo expression studies using Northern blots and reverse transcriptase-PCR showed low PLD1 mRNA levels in...
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