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Article

Asc1, a WD-repeat protein, is required for hyphal development and virulence in Candida albicans.

Acta biochimica et biophysica Sinica - 1 Nov 2010

Liu Xiaoyan, Nie Xinyi, Ding Yufeng, Chen Jiangye

Abstract excerpt

Candida albicans is a human pathogenic fungus which can undergo a morphological transition from yeast to hyphae in response to a variety of environmental stimuli. We analyzed a C. albicans Asc1 (Absence of growth Suppressor of Cyp1) protein which is entirely composed of seven repeats of the WD domain, and is conserved from fungi to metazoan. Deleting the ASC1 in C. albicans led to a profound defect in hyphal...

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Source

Identifiers

PMID: 20929924
DOI: 10.1093/abbs/gmq093

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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