Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sex-Selective Effects on Behavior in a Mouse Model of Tuberous Sclerosis Complex.

eNeuro - 1 Jan 2000

Saré Rachel Michelle, Lemons Abigail, Figueroa Christopher, Song Alex, Levine Merlin, Beebe Smith Carolyn

Abstract excerpt

Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder that is caused by a mutation in either TSC1 or TSC2 TSC affects multiple systems of the body, and patients with TSC display a range of neurologic and behavioral manifestations including seizures, intellectual disability, autism spectrum disorders, attention deficit hyperactivity disorder, anxiety, and mood disorders. Whereas behavioral...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disease Models, Animal
Share to Genotype
Share to Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phenotype

Share to Sex Factors

Share to Tuberous Sclerosis

Share to Tuberous Sclerosis Complex 2 Protein

Source

Open in PubMed Open full text

Identifiers

PMID: 32303566
DOI: 10.1523/ENEURO.0379-19.2020
PMCID: PMC7196723

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sex-Selective Effects on Behavior in a Mouse Model of Tuberous Sclerosis Complex.PMID 32303566Read ↗

Increased levels of anxiety-related behaviors in a Tsc2 dominant negative transgenic mouse model of tuberous sclerosis.Semantic proximity Read ↗

Tsc2 mutation rather than Tsc1 mutation dominantly causes a social deficit in a mouse model of tuberous sclerosis complexSemantic proximity Read ↗

Tsc2 mutation rather than Tsc1 mutation dominantly causes a social deficit in a mouse model of tuberous sclerosis complex.Semantic proximity Read ↗

Chromosomal and gonadal sex have differing effects on social motivation in miceSemantic proximity Read ↗

Altered ultrasonic vocalizations in a tuberous sclerosis mouse model of autismSemantic proximity Read ↗

Aberrant TSC-Rheb axis in Oxytocin receptor+ cells mediate stress-induced anxietySemantic proximity Read ↗

Impaired social interactions and motor learning skills in tuberous sclerosis complex model mice expressing a dominant/negative form of tuberinSemantic proximity Read ↗

Research resource: loss of the steroid receptor coactivators confers neurobehavioral consequences.Semantic proximity Read ↗

Decreased aggression and increased repetitive behavior in Pten haploinsufficient mice.Semantic proximity Read ↗

Sex‐Specific Behavioral Features of Juvenile and Adult Haploinsufficient Scn2a +/− Female Mice, Model of Autism Spectrum DisorderSemantic proximity Read ↗

Cognitive deficits in Tsc1+/- mice in the absence of cerebral lesions and seizures.Semantic proximity Read ↗

Reversal of learning deficits in a Tsc2+/− mouse model of tuberous sclerosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.