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Article

Involvement of calcium-sensing receptor in osteoblastic differentiation of mouse MC3T3-E1 cells.

American journal of physiology. Endocrinology and metabolism - 1 Mar 2005

Yamauchi Mika, Yamaguchi Toru, Kaji Hiroshi, Sugimoto Toshitsugu, Chihara Kazuo

Abstract excerpt

We have previously shown that the extracellular calcium-sensing receptor (CaR) is expressed in various bone marrow-derived cell lines and plays an important role in stimulating their proliferation and chemotaxis. It has also been reported that the CaR modulates matrix production and mineralization in chondrogenic cells. However, it remains unclear whether the CaR plays any role in regulating osteoblast...

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PMID: 15547142
DOI: 10.1152/ajpendo.00229.2004

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